Ebola virus disease

-Ebola virus is a single-stranded, nonsegmented, negative-polarity RNA virus

-It causes Ebola hemorrhagic fever (EHF)

-the virions have ‘shepherd’s crook’ appearance 

Symptoms & Signs 

-Transmission from human to human occurs via blood and body fluids

-Fever, headache, sore throat, myalgia, arthralgia, vomiting, diarrhea, rash, uveitis, shock, multiorgan failure 


-Virus is detected with a real-time RT-PCR, ELISA, and IgM antibody serum tests 


-There are no approved antiviral medications for treatment of Ebola virus disease

-Supportive therapy with intravenous fluids and electrolytes 

Q. What are the most common complications of EVD? Hypovolemic shock and multiorgan failure