Granuloma inguinale

Granuloma inguinale is a rare, chronic, granulomatous, progressive ulcerative disease

-it is caused by the organism Klebsiella granulomatis (previously called Calymmatobacterium granulomatis)

-K. granulomatis is a facultative gram-negative, nonmotile, pleomorphic bacteria which resides in the cytoplasm of large mononuclear cells

-it mainly affects the genital and perigenital skin

-it is mainly contracted through sexual transmission

Symptoms & Signs 

-it occurs in four clinical types – ulcerogranulomatous (most common), hypertrophic, necrotic, and sclerotic

-Ulcerogranulomatous type presents as highly vascular, beefy-red ulcers that are nontender and bleed to the touch easily


Diagnosis confirmed by demonstrating intracellular cysts filled with bodies which stain deeply with Wright stain (Donovan bodies) on histology


Doxycycline, Azithromycin,Erythromycin or Ciprofloxacin