Group B Streptococcal infection is a gram-positive coccus infection which is an important cause of illness in infants, pregnant women

-It is a frequent cause of asymptomatic bacteriuria, urinary tract infection, upper genital tract infection (ie, intraamniotic infection or chorioamnionitis), postpartum endometritis, pneumonia, puerperal sepsis, and bacteremia without a focus.

-Asymptomatic bacteriuria is identified by screening urine cultures that are obtained during prenatal visits. At least one screening urine culture should be obtained during early pregnancy.

-Invasive maternal infection with GBS is associated with pregnancy loss and preterm delivery.

-Colonization of pregnant women by GBS is a major risk factor for neonatal GBS infection.

-Sterile urine must be documented after treatment, and periodic screening cultures should be obtained throughout the pregnancy to identify recurrent bacteriuria.

-Women with documented GBS bacteriuria should not be screened for GBS rectal/vaginal colonization later in pregnancy but should be considered persistently GBS colonized and receive intrapartum chemoprophylaxis at the time of delivery.

-Perform universal screening at 35 to 37 weeks.

-Women with any GBS bacteriuria should receive intrapartum chemoprophylaxis at the time of delivery to prevent neonatal infection

-Treat with antibiotics: Amoxicillin, penicillin, cephalexin, clindamycin