Staphylococcal Scalded Skin syndrome (SSSS)

SSSS is caused by hematogenous dissemination of exfoliative toxin produced by S.aureus, a toxin-producing staphylococcus

-Bullous impetigo is caused by the same exfoliative toxins when they affect the skin locally. 

-SSSS is most common in neonates and children under the age of 5 years

Symptoms & Signs: Tender, macular erythema develop abruptly over the face, axilla, and groin; as they spread, they form blisters over all parts of the body;  the blisters enlarge to slough and give ‘rolled up’ sandpaper-like texture to skin 

-Lateral traction of the skin reveals the splitting of the epidermis from the dermis (Nikolsky sign)

Diagnosis: can be established by skin biopsy and isolation of Staph aureus from the lesions 

Treatment: Antistaphylococcal antibiotics, intravenous fluids and supportive measures 

Healing occurs in 7 to 10 days.

Leave a Reply

Fill in your details below or click an icon to log in:

WordPress.com Logo

You are commenting using your WordPress.com account. Log Out /  Change )

Google photo

You are commenting using your Google account. Log Out /  Change )

Twitter picture

You are commenting using your Twitter account. Log Out /  Change )

Facebook photo

You are commenting using your Facebook account. Log Out /  Change )

Connecting to %s

This site uses Akismet to reduce spam. Learn how your comment data is processed.