Haemophilus influenza

Haemophilus influenzae are pleomorphic, oxidase positive, gram-negative coccobacilli rods that commonly colonize and infect the human respiratory tract. 

-H. influenzae are found on the mucous membranes of the upper respiratory tract in humans with the nasopharynx as the most common site of long-term colonization 

-Clinically, H. influenzae is similar to S. pneumoniae, with a slower onset.

-it is spread by airborne droplets or by direct contact with secretions or fomites. 

-its most serious manifestation is meningitis 

-the most prominent strain is Type b 

-risk factors include alcoholism, smoking, chronic lung disease, advanced age, and HIV infection 

Symptoms & Signs 

H influenzae may cause sinusitis, otitis, bronchitis, epiglottitis, pneumonia,pericarditis, cellulitis, arthritis, meningitis, and endocarditis. 


Diagnosis can be established by showing gram-negative coccobacilli in culture


Antibiotics: Beta-lactams (amoxicillin, amoxicillin-clavulanate), cephalosporins, fluoroquinolones, macrolides, and tetracyclines

-In Hib meningitis, administration of glucocorticoids reduces the incidence of neurologic sequelae 


All children should be immunized with an Hib conjugate vaccine with the primary series at 2–6 months of age, and a booster dose at 12–15 months of age.

Leave a Reply

Fill in your details below or click an icon to log in:

WordPress.com Logo

You are commenting using your WordPress.com account. Log Out /  Change )

Twitter picture

You are commenting using your Twitter account. Log Out /  Change )

Facebook photo

You are commenting using your Facebook account. Log Out /  Change )

Connecting to %s

This site uses Akismet to reduce spam. Learn how your comment data is processed.