Fascioliasis

Fascioliasis is an infectious disease caused by Fasciola hepatica, the sheep liver fluke

-it is prevalent in sheep-raising areas 

-it results from ingestion of encysted metacercariae on aquatic vegetables or water plants such as watercress 

Symptoms & Signs 

Fever, malaise, abdominal pain, weight loss, urticaria, marked eosinophilia, leukocytosis, tender hepatomegaly, cholangitis 

CT and other imaging studies show hypodense migratory lesions of the liver. 

Diagnosis 

Definitive diagnosis: Identification of characteristic eggs in stool, duodenal or biliary aspirates 

CT/imaging studies: hypodense nodules in the liver; tracts or tunnels (representing the migration of larvae)  

Treatment 

The treatment of choice is triclabendazole

Other effective agents: Bithionol, emetine, dehydroemetine, nitazoxanide 

-it does not respond well to praziquantel

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