Paragonimiasis is primarily a lung disease caused by the fluke paragonimus
-it is prevalent in Southeast Asia, Africa, and South and Central America.
-Human infection follows consumption of undercooked or raw crustaceans such as shellfish, crayfish and crabs
-After consumption, larvae enter the gut and later burrow through diaphragm into lung parenchyma
Symptoms & Signs
Lung disease: Fever, cough, chest pain, hemoptysis with rusty, blood-tinged sputum containing Charcot-Leyden crystals, dyspnea, bronchitis, bronchiectasis, lung abscess, urticaria, and eosinophilia
-Individuals may be mistaken for having tuberculosis
Extrapulmonary involvement: Blindness, epididymitis, testicular inflammation, and seizures
Diagnosis is made by finding the characteristic eggs in sputum, urine, or stool, or by identifying worms in biopsied tissues
-Serologic tests help in making diagnosis and monitoring treatment response
Chest X-ray: small segmental infiltrates, round nodules, cystic rings with a crescent corona, fibrosis, abscesses and calcifications
Skull imaging in CNS disease: clusters of calcified cysts, ring-enhancing lesions
The treatment of choice is praziquantel or triclabendazole.