Sporotrichosis

Introduction 

Sporotrichosis is a chronic granulomatous fungal infection caused by Sporothrix schenckii

-it is common among gardeners, florists and agriculture workers 

-Infection occurs when the organism is inoculated into the skin during gardening or puncture from a rose thorn 

S. schenckii is a thermally dimorphic fungus which produces branching, septate hyphae and conidia 

Symptoms & Signs 

Sporotrichosis has four clinical presentations: 

Fixed: a painless nodule or plaque that may become pustular or ulcerated or verrucous plaque; most common on dorsum of hand or finger

Lymphocutaneous:  Erythematous nodules in a linear array in lymphatic channels mostly on the dorsum of the hand and forearm

Pulmonary: inhalation of conidiospores producing pulmonary infection 

Disseminated:  From lungs,it disseminates hematogenously to joints, eyes and meninges 

Diagnosis 

Histology: Granulomatous microabscesses 

Culture: Most reliable method of diagnosis 

Treatment 

Itraconazole, fluconazole, terbinafine, Amphotericin B, potassium iodide 

Leave a Reply

Fill in your details below or click an icon to log in:

WordPress.com Logo

You are commenting using your WordPress.com account. Log Out /  Change )

Google photo

You are commenting using your Google account. Log Out /  Change )

Twitter picture

You are commenting using your Twitter account. Log Out /  Change )

Facebook photo

You are commenting using your Facebook account. Log Out /  Change )

Connecting to %s

This site uses Akismet to reduce spam. Learn how your comment data is processed.