Introduction
Sporotrichosis is a chronic granulomatous fungal infection caused by Sporothrix schenckii
-it is common among gardeners, florists and agriculture workers
-Infection occurs when the organism is inoculated into the skin during gardening or puncture from a rose thorn
S. schenckii is a thermally dimorphic fungus which produces branching, septate hyphae and conidia
Symptoms & Signs
Sporotrichosis has four clinical presentations:
Fixed: a painless nodule or plaque that may become pustular or ulcerated or verrucous plaque; most common on dorsum of hand or finger
Lymphocutaneous: Erythematous nodules in a linear array in lymphatic channels mostly on the dorsum of the hand and forearm
Pulmonary: inhalation of conidiospores producing pulmonary infection
Disseminated: From lungs,it disseminates hematogenously to joints, eyes and meninges
Diagnosis
Histology: Granulomatous microabscesses
Culture: Most reliable method of diagnosis
Treatment
Itraconazole, fluconazole, terbinafine, Amphotericin B, potassium iodide